Tutorial: Saving Multiple Images to Target File Size for Kindle MOBI

In a recent project, I converted a graphic novel originally destined for print to EPUB and Kindle (MOBI) formats. The author/illustrator reformatted any spreads to work on single pages, and provided me with nearly 300 images, each each of which would be a single page in the ebook. Rather than creating a fixed-layout ebook, I found the more efficient route in terms of was to create a regular reflowable ebook in EPUB format, then after filling out the metadata and adding various code tweaks, converting it to Kindle format using Calibre.